UrineCheck 6 has been designed to determine whether any manipulation has been done in the urine sample provided by the donor. It detects the presence of any substance added to the urine. UrineCheck 6 Drug Adulteration test strip makes use of creatinine for checking whether the urine sample has been diluted. The reaction between creatinine and a creatinine indicator under alkaline conditions is studied, which gives rise to a substance that is purplish-brown in color. The deeper the color, the higher is the creatinine concentration. The kit makes use of Glutaraldehyde for determining whether exogenous aldehyde is present in the sample. The reaction between the aldehyde group of the glutaraldehyde and an indicator is studied for this purpose. This gives rise to the formation of a pink-colored substance. The kit also helps in determining whether exogenous nitrite is present in the sample. The reaction between nitrite and aromatic amine in acid gives rise to a diazonium compound. The reaction of this compound with an indicator gives rise to the formation of pinkish-red colored oxidants. For determining whether oxidizing reagents are present in the sample, the reaction between a color indicator and various oxidants are studied. These oxidants can be either bleach, hydrogen peroxide or pyridinium chlorochromate. This gives rise to the formation of a complex that is blue in color. Other colors give an idea of whether other oxidants pH are present in the sample. This kit can also be used to test whether acidic or alkaline adulterant is present in the urine sample. The double pH indicator method is used for determining this. This renowned test studies the appearance of various colors ranging from orange and yellow to green and blue. These colors give an idea of the level of pH. Orange indicates low pH, while blue indicates high pH. The principle of specific gravity is used to study whether the sample has been diluted. The concept behind this test is the pKa change of some polyelectrolytes that have been pretreated that takes place with ionic concentration. When the ionic concentration is low, the color ranges from dark blue to blue-green. Conversely, when the ionic concentration is high, the color ranges from green to yellow. |
